Muhammad Arba
Identitas Diri
| Nama lengkap | : | Prof. Dr. Muhammad Arba, S.Si., M.Si |
| Jenis kelamin | : | Laki-laki |
| Jabatan fungsional | : | Lektor Kepala |
| NIP | : | 19811129 200812 1 001 |
| NIDN | : | 0029118101 |
| Tempat dan Tanggal lahir | : | Tombula/29 November 1981 |
| : | muh.arba@uho.ac.id | |
| Nomor Telepon/HP | : | 0811 405 6877 |
| Alamat Kantor | : | Fakultas Farmasi, Universitas Halu Oleo |
| Nomor Telepon/Faks | : | 0401-3191929/0401-3194096 |
| Lulusan yang telah dihasilkan | : | S-1=75 orang |
| Profil Scopus | : | https://www.scopus.com/authid/detail.uri?authorId=57155296400 |
| Profil SINTA | : | https://sinta.ristekbrin.go.id/authors/detail?id=257944&view=overview |
| Profil Google Scholar | : | https://scholar.google.com/citations?user=rt3FG0kAAAAJ&hl=en
|
Riwayat Pendidikan
| S-1 | S-2 | S-3 | |
| Nama Perguruan tinggi | Universitas Halu Oleo (UHO) | Institut Teknologi Bandung (ITB) | Institut Teknologi Bandung (ITB) |
| Bidang ilmu | Kimia | Kimia Fisika | Analisis Farmasi dan Kimia Medisinal |
| Tahun masuk-lulus | 2000-2004 | 2006-2008 | 2010-2015 |
- Pengalaman Penelitian Dalam Lima Tahun Terakhir
| No | Tahun | Judul Penelitian | Sumber Pendanaan |
| 1. | 2020-2021 | Skrining Tanaman Obat Sulawesi Tenggara untuk Penanganan Coronavirus Disease 2019 (Covid-19) berbasis Desain Obat Rasional | DRPM-Kemenristek-Dikti |
| 2. | 2019-2020 | Kajian Potensi Senyawa Turunan Porfirin Sebagai Inhibitor Phosphatidylinositol 3-Kinase (Pi3k) Dan Bruton’s Tyrosine Kinase (Btk) Untuk Penanganan Penyakit Kanker | DRPM-Kemenristek-Dikti |
| 3. | 2018-2019 | Kajian Senyawa Turunan Porfirin Sebagai Inhibitor B-Cell Lymphoma 2 (Bcl-2) Dan Vascular Endothelial Growth Factor Receptor 2 (Vegfr-2) | DRPM-Kemenristek-Dikti |
| 4. | 2017-2018 | Pengembangan Inhibitor Proteasome Berbasis Porfirin | DRPM-Kemenristek-Dikti |
| 5. | 2016-2017 | Studi Selektivitas dan Potensi Senyawa Turunan Porfirin Sebagai Inhibitor Cyclin-Dependent Kinase-2 (CDK-2) dan Topoisomerase I | DRPM-Kemenristek-Dikti |
| 6. | 2015 | Analisis Interaksi Hibrid Kationik Porfirin dengan G-Kuadrupleks Paralel, Antiparalel, dan Campuran Paralel/Antiparalel dan Implikasinya terhadap Desain Obat Anti Kanker | DRPM-Kemenristek-Dikti |
| 7. | 2010 | Studi Teoritis dan Eksperimental Interaksi Senyawa Hibrid kationik Porfirin-Antrakuinon dengan DNA | Dikti |
Pengalaman Pengabdian kepada Masyarakat Dalam Lima Tahun Terakhir
| No | Tahun | Judul Pengabdian Kepada Masyarakat | Sumber Pendanaan |
| 1. | 2020 | Penguatan Peran Warga Masyarakat Dalam Mitigasi dan Adaptasi Menghadapi Wabah Covid-19 di Kabupaten Konawe | DIPA Univ. Halu Oleo |
| 2. | 2016 | Sosialisasi pencegahan Penyalahgunaan narkoba pada Siswa SMA se kabupaten Buton tengah | DIPA Univ. Halu Oleo |
| 3. | 2015 | Bimbingan Teknis Pembuatan Sistim Pengolahan Air Minum Menggunakan Sistim Aerasi Filtrasi bagi Masyarakat Kelurahan “Pengabdian Dosen Terintegrasi KKN Tematik" | DIPA Univ. Halu Oleo |
Publikasi Artikel Ilmiah dalam Jurnal dalam 5 tahun Terakhir
| No | Judul Artikel Ilmiah | Nama Jurnal (Penerbit, Quartile) | Volume/Nomor/Tahun |
| 1. | GC-MS, LC-MS/MS, Docking and Molecular Dynamics Approaches to Identify Potential SARS-CoV-2 3-Chymotrypsin-like Protease Inhibitors from Zingibir officinale Roscoe | Molecules (MDPI, Q2) | 26/5230, 2021 |
| 2. | Determination of Antiradical Activity, Total Phenolic and Flavonoid Contents of Kamena-mena (Clerodendrum paniculatum. L) Leaves | Trop J Nat Prod Res (University of Benin, Q4) | 5(2):287-293, 2021 |
| 3. | Determination of antiradical activity and phenolic and flavonoid contents of extracts and fractions of jackfruit (Artocarpus heterophyllus Lamk) seeds | Food Research (Runnye Lyan Resources, Q4) | 5(3): 36 – 43, 2021 |
| 4. | Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2 | Computers in Biology and Medicine (Elsevier, Q1) | 129/2021 |
| 5. | In Vitro and In Silico Studies of Quercetin and Daidzin as Selective Anticancer Agents | Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3) |
21/2021 |
| 6. | Free Radical Scavenging Activity of extract and fraction of Okra seeds
determined by DPPH (2,2-diphenyl-1-picrylhydrazy) method |
Research Journal of Pharmacy and Technology (Q3) | 14/4/2021 |
| 7. | Virtual Screening of the Indonesian Medicinal Plant and Zinc Databases for Potential Inhibitors of the RNA-Dependent RNA Polymerase (RdRp) of 2019 Novel Coronavirus | Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3) |
20/6/2020 |
| 8. | Molecular Modeling on the Identification of Potential Janus Kinase 3 (JAK3) Inhibitors Based on the Indonesian
Medicinal Plant Database |
Journal of Mathematical and Fundamental Sciences (Institut Teknologi Bandung, Q3) | 52/3/2020 |
| 9. | Identification of Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor: Pharmacophore-based Virtual Screening and Molecular Dynamics Simulation | Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3) |
20/5/2020 |
| 10. | Antihyperlipidemic Effect of Ethanol Extract of Lansau a Traditional Medicine of Muna Ethnic, Indonesia | Biointerface Research in Applied Chemistry (Q4) | 10/6/2020 |
| 11. | Structure-based Pharmacophore Modelling for identifying VEGFR2 Inhibitor | Research Journal of Pharmacy and Technology (Q3) | 13/7/2020 |
| 12. | Identification of potential inhibitors for Bruton’s Tyrosine Kinase (BTK) based on pharmacophore-based virtual screening | Biointerface Research in Applied Chemistry (Q4) | 10/3/2020 |
| 13. | The search for peptide deformylase inhibitor from Indonesian Medicinal Plant Database: an in-silico investigation | Biointerface Research in Applied Chemistry (Q4) | 10/2/2020 |
| 14. | Radical scavenging assay and determination Flavonoid and Phenolic total of extract and Fractions of Raghu bark (Dracontomelon dao (Blanco) Merr) | Research Journal of Pharmacy and Technology (Q3) | 13/5/2020 |
| 15. | Identification of polyketide synthase 13 inhibitor: Pharmacophore-based virtual screening and molecular dynamics simulation | Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 9/07/2019 |
| 16. | 3D-QSAR, molecular docking and dynamics simulation of difluorophenol pyridine derivatives as RSK2 inhibitor | Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 9/06/2019 |
| 17. | 3D-QSAR, molecular docking, and dynamics simulation of
quinazoline–phosphoramidate mustard conjugates as EGFR inhibitor |
Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 9/01/2019 |
| 18. | Computational approach toward targeting the interaction of porphyrin derivatives with Bcl-2 | Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 8/12/2018 |
| 19. | Molecular modeling of 4-fluoropyrrolidine-2-carbonitrile and
octahydrocyclopenta[b]pyrrole-2-carbonitrile as a dipeptidyl peptidase IV (DPP4) inhibitor |
Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 8/10/2018 |
| 20. | Insight into the Interaction of Cationic Porphyrin-Anthraquinone Hybrids with Hsp90: In Silico Analysis | Journal of Mathematical and Fundamental Sciences (Institut Teknologi Bandung, Q3) | 50/3/2018 |
| 21. | Pharmacophore-based virtual screening for identifying β5 subunit inhibitor
of 20S proteasome |
Computational Bioology and Chemistry (Elsevier, Q1) | 77/2018 |
| 22. | Molecular modeling on porphyrin derivatives as β5 subunit inhibitor of
20S proteasome |
Computational Bioology and Chemistry (Elsevier, Q1) | 74/2018 |
| 23. | QSAR, Molecular Docking and Dynamics Studies of Quinazoline
Derivatives as Inhibitor of Phosphatidylinositol 3-Kinase |
Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 8/5/2018 |
| 24. | Hubungan Kuantitatif Struktur-Aktivitas (HKSA) dan Penambatan Molekul Senyawa Turunan Benzamida sebagai Inhibitor Alosterik Mitogen Enhanced Kinase (MEK) | Jurnal Kimia VALENSI: Jurnal Penelitian dan Pengembangan Ilmu Kimia (Sinta 2) | 4/1/2018 |
| 25. | Molecular modeling of cationic porphyrin-anthraquinone hybrids as DNA topoisomerase II inhibitors |
Computational Bioology and Chemistry (Elsevier, Q1) | 71/2017 |
| 26. | QSAR, Molecular Docking and Molecular Dynamics Studies of Pyrrolo[2,3-b]pyridine Derivatives as Bruton’s Tyrosine Kinase Inhibitors | Journal of Applied Pharmaceutical Science (Medipoeia, Q3) | 7/12/2017 |
| 27. | In silico Study of Porphyrin-Anthraquinone Hybrids as CDK2 Inhibitor | Computational Bioology and Chemistry (Elsevier, Q1) | 67/1/2017 |
| 28. | Molecular Docking and Molecular Dynamics Simulations on the Interaction of Cationic Porphyrin-Anthraquinone Hybrids with DNA G-quadruplexes | Journal of Biomolecular Structure and Dynamics (Taylor & Francis, Q3) | 34/2/2016 |
| 29. | Studi Hubungan Kuantitatif Struktur-Aktivitas Senyawa Turunan Meisoindigo Sebagai Inhibitor CDK4 | Journal Kimia Riset (Sinta 4) | 1/2/2016 |
| 30. | The Binding Modes of Cationic Porphyrin-Anthraquinone Hybrids to DNA Duplexes: In Silico Study | Journal of Biomolecular Structure and Dynamics (Taylor & Francis, Q3) | 33/3/2015 |
| 31. | Differences in excitation energy transfer of Arthrospira platensis cells grown in seawater medium and freshwater medium, probed by time-resolved fluorescence spectroscopy | Chemical Physics Letters (Elsevier, Q2)
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588/19/2013
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Pengalaman Menulis Buku dalam 5 tahun Terakhir
| No | Judul Buku | Nama Penerbit | Tahun |
| 1. | Buku Ajar Farmasi Komputasi (Buku Wajib MK Farmasi Komputasi di Fakultas Farmasi Universitas Halu Oleo) | Deepublish, Yogyakarta | 2019 |
Pemakalah Seminar Ilmiah (Oral Presentation) dalam 5 Tahun Terakhir
| No | Nama Pertemuan Ilmiah/Seminar | Judul Artikel Ilmiah | Waktu dan Tempat |
| 1. | 5th IAPC Meeting Emerging Technologies in Drug Discovery and Development" | Quantitative structure activity relationship (QSAR) analysis of Indirubin derivatives as cyclin dependent kinase 5 (CDK5) inhibitor | 30-31 Agustus 2016, Zhuhai, China |
| 2. | 10th AFMC International Medicinal Chemistry Symposium | The Binding Preference of Cationic Porphyrin- Anthraquinone Hybrids to Parallel Over Antiparallel and Mixed-Hybrid DNA G-Quadruplexes: A Computational Study | 18-21 November 2015, Jeju, Korea Selatan |
| 3. | The 3rd International Conference on Conmputation for Science and Technology | Molecular Docking and Molecular Dynamics Simulation of the Interaction of Cationic Imidazolium Porphyrin-Anthraquinone and Hsp90 |
23-25 September 2014, Bali, Indonesia
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- G. Penghargaan dalam 10 Tahun terakhir
| No | Jenis Penghargaan | Institusi Pemberi Penghargaan | Tahun |
| 1. | World Class Professor (WCP) | Kemendikbud-RistekDikti | 2021 |
| 2. | Satyalencana Karya Satya 10 tahun
|
Presiden RI | 2020 |
| 3. | Dosen terbaik tingkat Universitas Halu Oleo | Universitas Halu Oleo | 2018 |
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