Sekretaris LPPMP UHO

Muhammad Arba

Identitas Diri

Nama lengkap : Dr. Muhammad Arba, S.Si., M.Si
Jenis kelamin : Laki-laki
Jabatan fungsional : Lektor Kepala
NIP : 19811129 200812 1 001
NIDN : 0029118101
Tempat dan Tanggal lahir : Tombula/29 November 1981
Email : muh.arba@uho.ac.id
Nomor Telepon/HP : 0811 405 6877
Alamat Kantor : Fakultas Farmasi, Universitas Halu Oleo
Nomor Telepon/Faks : 0401-3191929/0401-3194096
Lulusan yang telah dihasilkan : S-1=75 orang
Profil Scopus : https://www.scopus.com/authid/detail.uri?authorId=57155296400
Profil SINTA : https://sinta.ristekbrin.go.id/authors/detail?id=257944&view=overview
Profil Google Scholar : https://scholar.google.com/citations?user=rt3FG0kAAAAJ&hl=en

 

 

 Riwayat Pendidikan

S-1 S-2 S-3
Nama Perguruan tinggi Universitas Halu Oleo (UHO) Institut Teknologi Bandung (ITB) Institut Teknologi Bandung (ITB)
Bidang ilmu Kimia Kimia Fisika Analisis Farmasi dan Kimia Medisinal
Tahun masuk-lulus 2000-2004 2006-2008 2010-2015

 

  1. Pengalaman Penelitian Dalam Lima Tahun Terakhir
No Tahun Judul Penelitian Sumber Pendanaan
1. 2020-2021 Skrining Tanaman Obat Sulawesi Tenggara untuk Penanganan Coronavirus Disease 2019 (Covid-19) berbasis Desain Obat Rasional DRPM-Kemenristek-Dikti
2. 2019-2020 Kajian Potensi Senyawa Turunan Porfirin Sebagai Inhibitor Phosphatidylinositol 3-Kinase (Pi3k) Dan Bruton’s Tyrosine Kinase (Btk) Untuk Penanganan Penyakit Kanker DRPM-Kemenristek-Dikti
3. 2018-2019 Kajian Senyawa Turunan Porfirin Sebagai Inhibitor B-Cell Lymphoma 2 (Bcl-2) Dan Vascular Endothelial Growth Factor Receptor 2 (Vegfr-2) DRPM-Kemenristek-Dikti
4. 2017-2018 Pengembangan Inhibitor Proteasome Berbasis Porfirin DRPM-Kemenristek-Dikti
5. 2016-2017 Studi Selektivitas dan Potensi Senyawa Turunan Porfirin Sebagai Inhibitor Cyclin-Dependent Kinase-2 (CDK-2) dan Topoisomerase I DRPM-Kemenristek-Dikti
6. 2015 Analisis Interaksi Hibrid Kationik Porfirin dengan G-Kuadrupleks Paralel, Antiparalel, dan Campuran Paralel/Antiparalel dan Implikasinya terhadap Desain Obat Anti Kanker DRPM-Kemenristek-Dikti
7. 2010 Studi Teoritis dan Eksperimental Interaksi Senyawa Hibrid kationik Porfirin-Antrakuinon dengan DNA Dikti

Pengalaman Pengabdian kepada Masyarakat Dalam Lima Tahun Terakhir

No Tahun Judul Pengabdian Kepada Masyarakat Sumber Pendanaan
1. 2020 Penguatan Peran Warga Masyarakat Dalam Mitigasi dan Adaptasi Menghadapi Wabah Covid-19 di Kabupaten Konawe DIPA Univ. Halu Oleo
2. 2016 Sosialisasi pencegahan Penyalahgunaan narkoba pada Siswa SMA se kabupaten Buton tengah DIPA Univ. Halu Oleo
3. 2015 Bimbingan Teknis Pembuatan Sistim Pengolahan Air Minum Menggunakan Sistim Aerasi Filtrasi bagi Masyarakat Kelurahan “Pengabdian Dosen Terintegrasi KKN Tematik” DIPA Univ. Halu Oleo

 Publikasi Artikel Ilmiah dalam Jurnal dalam 5 tahun Terakhir

No Judul Artikel Ilmiah Nama Jurnal (Penerbit, Quartile) Volume/Nomor/Tahun
1. GC-MS, LC-MS/MS, Docking and Molecular Dynamics Approaches to Identify Potential SARS-CoV-2 3-Chymotrypsin-like Protease Inhibitors from Zingibir officinale Roscoe Molecules (MDPI, Q2) 26/5230, 2021
2. Determination of Antiradical Activity, Total Phenolic and Flavonoid Contents of Kamena-mena (Clerodendrum paniculatum. L) Leaves Trop J Nat Prod Res (University of Benin, Q4) 5(2):287-293, 2021
3. Determination of antiradical activity and phenolic and flavonoid contents of extracts and fractions of jackfruit (Artocarpus heterophyllus Lamk) seeds Food Research (Runnye Lyan Resources, Q4) 5(3): 36 – 43, 2021
4. Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2 Computers in Biology and Medicine (Elsevier, Q1) 129/2021
5. In Vitro and In Silico Studies of Quercetin and Daidzin as Selective Anticancer Agents Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3)  

21/2021

6. Free Radical Scavenging Activity of extract and fraction of Okra seeds

determined by DPPH (2,2-diphenyl-1-picrylhydrazy) method

Research Journal of Pharmacy and Technology (Q3) 14/4/2021
7. Virtual Screening of the Indonesian Medicinal Plant and Zinc Databases for Potential Inhibitors of the RNA-Dependent RNA Polymerase (RdRp) of 2019 Novel Coronavirus Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3)  

20/6/2020

8. Molecular Modeling on the Identification of Potential Janus Kinase 3 (JAK3) Inhibitors Based on the Indonesian

Medicinal Plant Database

Journal of Mathematical and Fundamental Sciences (Institut Teknologi Bandung, Q3) 52/3/2020
9. Identification of Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor: Pharmacophore-based Virtual Screening and Molecular Dynamics Simulation Indonesian Journal of Chemistry (Universitas Gajah Mada, Q3)  

20/5/2020

10. Antihyperlipidemic Effect of Ethanol Extract of Lansau a Traditional Medicine of Muna Ethnic, Indonesia Biointerface Research in Applied Chemistry (Q4) 10/6/2020
11. Structure-based Pharmacophore Modelling for identifying VEGFR2 Inhibitor Research Journal of Pharmacy and Technology (Q3) 13/7/2020
12. Identification of potential inhibitors for Bruton’s Tyrosine Kinase (BTK) based on pharmacophore-based virtual screening Biointerface Research in Applied Chemistry (Q4) 10/3/2020
13. The search for peptide deformylase inhibitor from Indonesian Medicinal Plant Database: an in-silico investigation Biointerface Research in Applied Chemistry (Q4) 10/2/2020
14. Radical scavenging assay and determination Flavonoid and Phenolic total of extract and Fractions of Raghu bark (Dracontomelon dao (Blanco) Merr) Research Journal of Pharmacy and Technology (Q3) 13/5/2020
15. Identification of polyketide synthase 13 inhibitor: Pharmacophore-based virtual screening and molecular dynamics simulation Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 9/07/2019
16. 3D-QSAR, molecular docking and dynamics simulation of difluorophenol pyridine derivatives as RSK2 inhibitor Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 9/06/2019
17. 3D-QSAR, molecular docking, and dynamics simulation of

quinazoline–phosphoramidate mustard conjugates as EGFR inhibitor

Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 9/01/2019
18. Computational approach toward targeting the interaction of porphyrin derivatives with Bcl-2 Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 8/12/2018
19. Molecular modeling of 4-fluoropyrrolidine-2-carbonitrile and

octahydrocyclopenta[b]pyrrole-2-carbonitrile as a dipeptidyl

peptidase IV (DPP4) inhibitor

Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 8/10/2018
20. Insight into the Interaction of Cationic Porphyrin-Anthraquinone Hybrids with Hsp90: In Silico Analysis Journal of Mathematical and Fundamental Sciences (Institut Teknologi Bandung, Q3) 50/3/2018
21. Pharmacophore-based virtual screening for identifying β5 subunit inhibitor

of 20S proteasome

Computational Bioology and Chemistry (Elsevier, Q1) 77/2018
22. Molecular modeling on porphyrin derivatives as β5 subunit inhibitor of

20S proteasome

Computational Bioology and Chemistry (Elsevier, Q1) 74/2018
23. QSAR, Molecular Docking and Dynamics Studies of Quinazoline

Derivatives as Inhibitor of Phosphatidylinositol 3-Kinase

Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 8/5/2018
24. Hubungan Kuantitatif Struktur-Aktivitas (HKSA) dan Penambatan Molekul Senyawa Turunan Benzamida sebagai Inhibitor Alosterik Mitogen Enhanced Kinase (MEK) Jurnal Kimia VALENSI: Jurnal Penelitian dan Pengembangan Ilmu Kimia (Sinta 2) 4/1/2018
25. Molecular modeling of cationic
porphyrin-anthraquinone hybrids as DNA topoisomerase II inhibitors
Computational Bioology and Chemistry (Elsevier, Q1) 71/2017
26. QSAR, Molecular Docking and Molecular Dynamics Studies of Pyrrolo[2,3-b]pyridine Derivatives as Bruton’s Tyrosine Kinase Inhibitors Journal of Applied Pharmaceutical Science (Medipoeia, Q3) 7/12/2017
27. In silico Study of Porphyrin-Anthraquinone Hybrids as CDK2 Inhibitor Computational Bioology and Chemistry (Elsevier, Q1) 67/1/2017
28. Molecular Docking and Molecular Dynamics Simulations on the Interaction of Cationic Porphyrin-Anthraquinone Hybrids with DNA G-quadruplexes Journal of Biomolecular Structure and Dynamics (Taylor & Francis, Q3) 34/2/2016
29. Studi Hubungan Kuantitatif Struktur-Aktivitas Senyawa Turunan Meisoindigo Sebagai Inhibitor CDK4 Journal Kimia Riset (Sinta 4) 1/2/2016
30. The Binding Modes of Cationic Porphyrin-Anthraquinone Hybrids to DNA Duplexes: In Silico Study Journal of Biomolecular Structure and Dynamics (Taylor & Francis, Q3) 33/3/2015
31. Differences in excitation energy transfer of Arthrospira platensis cells grown in seawater medium and freshwater medium, probed by time-resolved fluorescence spectroscopy Chemical Physics Letters (Elsevier, Q2)

 

588/19/2013

 

Pengalaman Menulis Buku dalam 5 tahun Terakhir

No Judul Buku Nama Penerbit Tahun
1. Buku Ajar Farmasi Komputasi (Buku Wajib MK Farmasi Komputasi di Fakultas Farmasi Universitas Halu Oleo) Deepublish, Yogyakarta 2019

Pemakalah Seminar Ilmiah (Oral Presentation) dalam 5 Tahun Terakhir

No Nama Pertemuan Ilmiah/Seminar Judul Artikel Ilmiah Waktu dan Tempat
1. 5th IAPC Meeting Emerging Technologies in Drug Discovery and Development” Quantitative structure activity relationship (QSAR) analysis of Indirubin derivatives as cyclin dependent kinase 5 (CDK5) inhibitor 30-31 Agustus 2016, Zhuhai, China
2. 10th AFMC International Medicinal Chemistry Symposium The Binding Preference of Cationic Porphyrin-   Anthraquinone Hybrids to Parallel Over Antiparallel and Mixed-Hybrid DNA G-Quadruplexes: A Computational Study 18-21 November 2015, Jeju, Korea Selatan
3. The 3rd International Conference on Conmputation for Science and Technology Molecular Docking and Molecular Dynamics Simulation of the Interaction of Cationic Imidazolium Porphyrin-Anthraquinone and Hsp90  

23-25 September 2014, Bali, Indonesia

 

 

  1. G. Penghargaan dalam 10 Tahun terakhir

 

No Jenis Penghargaan Institusi Pemberi Penghargaan Tahun
1. World Class Professor (WCP) Kemendikbud-RistekDikti 2021
2. Satyalencana Karya Satya 10 tahun

 

Presiden RI 2020
3. Dosen terbaik tingkat Universitas Halu Oleo Universitas Halu Oleo 2018

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